BDBM50399827 CHEMBL2180274

SMILES COC(=O)C1=C(C)N=C2CC(C)(C)CC(=O)C2C1c1cccc(c1)-c1ccc2[nH]ccc2c1

InChI Key InChIKey=DBRYDKANPLQESA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50399827   

TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50399827(CHEMBL2180274)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50399827(CHEMBL2180274)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50399827(CHEMBL2180274)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed