BDBM50399539 CHEMBL2180605

SMILES CNC(=O)c1cccc2c1ccc(c2)Oc3ccnc4c3cc(c(c4)OCC5(CC5)N)OC

InChI Key InChIKey=CUDVHEFYRIWYQD-UHFFFAOYSA-N

Data  25 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50399539   

TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 238nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 83nMAssay Description:Inhibition of FGFR2 (unknown origin) in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 18nMAssay Description:Inhibition of FGFR1 (unknown origin) in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR3 (unknown origin) in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGFR2 (unknown origin) in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR1 (unknown origin) in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 83nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 18nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 83nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 82.5nMAssay Description:Inhibition of FGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 18nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 83nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 18nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)
Affinity DataIC50: 17.5nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)