BDBM50398586 CHEMBL2177105::US8530504, 5

SMILES COCc1cc(OC)c(-c2c(C)sc3c(N(CC4CC4)CC4CCOCC4)c(C)nn23)c(OC)c1

InChI Key InChIKey=STIRPLJDIDQVGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398586   

TargetCorticotropin-releasing factor receptor 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50398586(CHEMBL2177105 | US8530504, 5)
Affinity DataIC50: 76nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2013
Entry Details
Go to US Patent

TargetCorticotropin-releasing factor receptor 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50398586(CHEMBL2177105 | US8530504, 5)
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed