BDBM50398077 CHEMBL1256178

SMILES NCCc1ccc(cc1)S(F)(=O)=O

InChI Key InChIKey=MGSKVZWGBWPBTF-UHFFFAOYSA-N

Data  6 IC50

PDB links: 24 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50398077   

TargetProthrombin(Human)
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398077(CHEMBL1256178)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of thrombin assessed as hydrolysis of H-D-Pro-L-Phe-L-Arg-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPlasminogen(Human)
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398077(CHEMBL1256178)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of plasmin assessed as hydrolysis of H-D-Val-L-Leu-L-Lys-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin G(Human)
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398077(CHEMBL1256178)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of cathepsin G assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTransmembrane protease serine 4(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50398077(CHEMBL1256178)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine protease HTRA1(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50398077(CHEMBL1256178)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant human HTRA1 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSerine protease HTRA2, mitochondrial(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50398077(CHEMBL1256178)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed