BDBM50397815 CHEMBL2177862

SMILES Cc1cc(N)n2nc(SCc3ccccc3)nc2n1

InChI Key InChIKey=YADKEMSSYKJABZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50397815   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50397815(CHEMBL2177862)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human dihydrofolate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydrofolate as substrate by DCIP-based colorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50397815(CHEMBL2177862)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human LSD1 (157 to 852 residues) expressed in Escherichia coli BL21(DE3) using H3K4me2 as substrate preincubated for 1 hr f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50397815(CHEMBL2177862)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red and horseradish peroxida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50397815(CHEMBL2177862)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed