BDBM50396978 CHEMBL2171171

SMILES CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCC=C)ncnc12

InChI Key InChIKey=IBFBTAMLGWTKQS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50396978   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396978(CHEMBL2171171)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant DOT1L catalytic domain amino acid (1 to 472) using [3H]-SAM after 30 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone-lysine N-methyltransferase SUV39H1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396978(CHEMBL2171171)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of SUV39H1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396978(CHEMBL2171171)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of CARM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396978(CHEMBL2171171)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of PRMT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed