BDBM50395943 CHEMBL2164544

SMILES Fc1cc(cc(c1)-c1nc(no1)-c1ccccn1)C#N

InChI Key InChIKey=GELAFISMURFRCA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50395943   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50395943(CHEMBL2164544)Copy SMILESCopy InChI

Affinity DataIC50: 25nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracel...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50395943(CHEMBL2164544)Copy SMILESCopy InChI

Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERG by IonWorks assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL