BDBM50395610 CHEMBL2165319

SMILES CN1C(=O)CCc2cc(c(OC3CCCC3)cc12)-c1cccnc1

InChI Key InChIKey=MOIMUBVZESBJEH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395610   

TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395610(CHEMBL2165319)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human CYP11B1 expressed in V79MZh cells using [14C]-11-deoxycorticosterone as substrate by HPTLC/phosphoimaging methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395610(CHEMBL2165319)
Affinity DataIC50: 759nMAssay Description:Inhibition of human CYP11B2 expressed in V79MZh cells using [14C]-11-deoxycorticosterone as substrate by HPTLC/phosphoimaging methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395610(CHEMBL2165319)
Affinity DataIC50: 22nMAssay Description:Inhibition of CYP19 in human placental microsomes using [1beta-3H]-androstendione as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395610(CHEMBL2165319)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed