BDBM50395460 CHEMBL2163638

SMILES CC(C)C(c1cc2CCN3c2c(CCC3=O)c1)n1ccnc1

InChI Key InChIKey=QFVWNWUBYUMAPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395460   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395460(CHEMBL2163638)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395460(CHEMBL2163638)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395460(CHEMBL2163638)
Affinity DataIC50: 500nMAssay Description:Inhibition of human placental CYP19 using androstenedione substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395460(CHEMBL2163638)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed