BDBM50395447 CHEMBL2163641

SMILES C=C(c1cc2CCN3c2c(CCC3=O)c1)n1ccnc1

InChI Key InChIKey=AHCDMEKROUDJMW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395447   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395447(CHEMBL2163641)
Affinity DataIC50: 100nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395447(CHEMBL2163641)
Affinity DataIC50: 19nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395447(CHEMBL2163641)
Affinity DataIC50: 17nMAssay Description:Inhibition of human placental CYP19 using androstenedione substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395447(CHEMBL2163641)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed