BDBM50394739 CHEMBL2165827

SMILES OCCNCCN1CCCc2cc(NC(=N)c3cccs3)ccc12

InChI Key InChIKey=NPCGRBLSVKLOQW-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394739   

LigandPNGBDBM50394739(CHEMBL2165827)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential assessed as reduction in tail current amplitude by conventional patch c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394739(CHEMBL2165827)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394739(CHEMBL2165827)
Affinity DataIC50: 3.29E+4nMAssay Description:Inhibition of human eNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394739(CHEMBL2165827)
Affinity DataIC50: 115nMAssay Description:Inhibition of human nNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed