BDBM50393774 CHEMBL2159335

SMILES CCCOc1ccc(cc1Cl)-c1cc(nn1C(C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=VEXHFZLCFRSPSZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393774   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50393774(CHEMBL2159335)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGastric inhibitory polypeptide receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50393774(CHEMBL2159335)
Affinity DataIC50: 478nMAssay Description:Antagonist activity at human GIPR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50393774(CHEMBL2159335)
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed