BDBM50393616 CHEMBL2158525

SMILES COc1cc(ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1)C1CCN(CCO)CC1

InChI Key InChIKey=SYZCXHIZVIOJHP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393616   

TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50393616(CHEMBL2158525)
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged human ALK cytoplasmic domain (1058-1620) expressed in Sf21 insect cells using GST-tagged human recombinant PLC-gamma/substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50393616(CHEMBL2158525)
Affinity DataIC50: 60nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed