BDBM50393277 CHEMBL2152032

SMILES Cc1cccc(Nc2nc(nnc2-c2ccccc2)-c2ccccn2)n1

InChI Key InChIKey=JQVHDQRNZLAXIV-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393277   

TargetHypoxia-inducible factor 1-alpha(Human)
The Broad Institute Probe Development Center

Curated by ChEMBL
LigandPNGBDBM50393277(CHEMBL2152032)
Affinity DataEC50:  2.24E+4nMAssay Description:Activation of human HIF1alpha expressed in DFX-induced human U2OS cells incubated for 30 mins prior to DFX-induction measured after overnight incubat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
The Broad Institute Probe Development Center

Curated by ChEMBL
LigandPNGBDBM50393277(CHEMBL2152032)
Affinity DataEC50:  5.41E+3nMAssay Description:Activation of GFP-tagged HIF1alpha expressed in human U2OS cells assessed as HIF1alpha nuclear translocation by high content imaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
The Broad Institute Probe Development Center

Curated by ChEMBL
LigandPNGBDBM50393277(CHEMBL2152032)
Affinity DataEC50:  7.55E+3nMAssay Description:Activation of human HIF1alpha expressed in human U2OS cells assessed as increase in VEGF expression by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed