BDBM50393246 CHEMBL2151440::US10214524, Example 130::US9067931, 130
SMILES COc1ccccc1-c1cccc2cc(oc12)C(=O)N[C@H]1CN2CCC1CC2
InChI Key InChIKey=GUUAJKBOCMZUJW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50393246
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at rat recombinant alpha7 nAChRMore data for this Ligand-Target Pair
Affinity DataEC50: 5.50E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus oocyteMore data for this Ligand-Target Pair
Affinity DataKi: 26nM ΔG°: -9.61kcal/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity to human recombinant 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Displacement of [3H]-MLA from alpha7 nAChR in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 62nM ΔG°: -9.13kcal/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair