BDBM50392793 CHEMBL2151323::US8486966, 12

SMILES CC(C)Oc1cc(n[nH]1)-n1cnc2cnc(N[C@@H](C)c3ncc(F)cn3)nc12

InChI Key InChIKey=ORGZROPLWGSXRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392793   

TargetHigh affinity nerve growth factor receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM50392793(CHEMBL2151323 | US8486966, 12)
Affinity DataIC50: 3nMT: 2°CAssay Description:To measure JAK2 kinase activity, a commercially available purified enzyme may be used. The enzyme may be a C-terminal His6-tagged, recombinant, human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM50392793(CHEMBL2151323 | US8486966, 12)
Affinity DataIC50: 3nMT: 2°CAssay Description:To measure JAK2 kinase activity, a commercially available purified enzyme may be used. The enzyme may be a C-terminal His6-tagged, recombinant, human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
Go to US Patent

LigandPNGBDBM50392793(CHEMBL2151323 | US8486966, 12)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed