BDBM50392790 CHEMBL2151320::US8486966, 16

SMILES C[C@H](Nc1ccc2ncn(-c3cc(C)[nH]n3)c2n1)c1ncc(F)cn1

InChI Key InChIKey=SKSNCQVCTOVJTO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392790   

TargetHigh affinity nerve growth factor receptor(Human)
Astrazeneca

US Patent

LigandBDBM50392790(CHEMBL2151320 | US8486966, 16)Copy SMILESCopy InChI

Affinity DataIC50: 61nMT: 2°CAssay Description:To measure JAK2 kinase activity, a commercially available purified enzyme may be used. The enzyme may be a C-terminal His6-tagged, recombinant, human...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/12/2013
Entry Details
Copy Entry DOIGo to US Patent

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TargetPotassium voltage-gated channel subfamily H member 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50392790(CHEMBL2151320 | US8486966, 16)Copy SMILESCopy InChI

Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
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