BDBM50392682 CHEMBL2151350

SMILES COc1ccc(cc1)C(=O)CC1(O)C(=O)NC(=O)NC1=O

InChI Key InChIKey=NYMLUNFPRGMRNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392682   

Target72 kDa type IV collagenase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50392682(CHEMBL2151350)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition measured after 3 hrs by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50392682(CHEMBL2151350)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant MMP9 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50392682(CHEMBL2151350)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of recombinant MMP8 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed