BDBM50392532 CHEMBL2152332
SMILES COc1ccc(C2=N[C@@H]([C@@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
InChI Key InChIKey=BDUHCSBCVGXTJM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50392532
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of MDM2 binding to p53More data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Inhibition of PMDM6-F peptide binding to MDM2 binding domain (1 to 118 residues) (unknown origin) by fluorescence polarization binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Binding affinity to MDM2 (1 to 118 residues) (unknown origin) assessed as inhibition constant incubated for 1 hr measured by fluorescence polarizatio...More data for this Ligand-Target Pair
Affinity DataKi: 198nMAssay Description:Inhibition of PMDM6-F probe binding to MDM2 (1 to 118 residues) (unknown origin) preincubated for 30 mins followed by PMDM6-F addition and measured a...More data for this Ligand-Target Pair