BDBM50392512 CHEMBL2152165

SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1

InChI Key InChIKey=DLEGYAJVPJEXJD-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50392512   

TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 630nMAssay Description:Inhibition of CETP-mediated [3H]cholesteryl ester transfer activity in human plasma after 2.5 hrs by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human recombinant CETP-mediated [3H]cholesteryl ester transfer from HDL to biotinylated LDL by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 630nMAssay Description:Inhibition of CETP in human whole plasma using [3H]-CE/HDL after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant CETP using [3H]-CE/HDL by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50392512(CHEMBL2152165)
Affinity DataIC50: 630nMAssay Description:Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed