BDBM50392121 CHEMBL2152632::US10874669, Compound (+-)-10

SMILES CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)C1CCc2nc(N)sc2C1

InChI Key InChIKey=YQJXEYCSOAXZLM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50392121   

TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50392121(CHEMBL2152632 | US10874669, Compound (+-)-10)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]spiroperidol from rat cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50392121(CHEMBL2152632 | US10874669, Compound (+-)-10)
Affinity DataKi:  1.92nMAssay Description:A well established radioligand competition assay was carried out to evaluate binding affinity of the test compounds and were compared with that of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Rat)
Wayne State University

US Patent
LigandPNGBDBM50392121(CHEMBL2152632 | US10874669, Compound (+-)-10)
Affinity DataKi:  46.7nMAssay Description:A well established radioligand competition assay was carried out to evaluate binding affinity of the test compounds and were compared with that of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Rat)
Wayne State University

US Patent
LigandPNGBDBM50392121(CHEMBL2152632 | US10874669, Compound (+-)-10)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]spiroperidol from rat cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed