BDBM50391237 CHEMBL5290216

SMILES CCn1c2ccccc2c2cc(ccc12)-n1nncc1-c1ccccc1

InChI Key InChIKey=VIFSSLHUQKUVOG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50391237   

TargetRas-related C3 botulinum toxin substrate 1(Human)
Lodz University of Technology

Curated by ChEMBL
LigandPNGBDBM50391237(CHEMBL5290216)
Affinity DataIC50: 100nMAssay Description:Inhibition of Rac1 GTPase in human breast cancer cell line treated for 24 hrs by western blot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCell division control protein 42 homolog(Human)
Lodz University of Technology

Curated by ChEMBL
LigandPNGBDBM50391237(CHEMBL5290216)
Affinity DataIC50: 80nMAssay Description:Inhibition of Cdc42 GTPase in human breast cancer cell line treated for 24 hrs by western blot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetRas-related C3 botulinum toxin substrate 3(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50391237(CHEMBL5290216)
Affinity DataIC50: 103nMAssay Description:Inhibition of Rac1/Rac2/Rac3 P21-binding domain in human MDA-MB-231 cells incubated for 24 hrs by pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCell division control protein 42 homolog(Human)
Lodz University of Technology

Curated by ChEMBL
LigandPNGBDBM50391237(CHEMBL5290216)
Affinity DataIC50: 78nMAssay Description:Inhibition of Cdc42 P21-binding domain in human MDA-MB-231 cells incubated for 24 hrs by pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCell division control protein 42 homolog(Human)
Lodz University of Technology

Curated by ChEMBL
LigandPNGBDBM50391237(CHEMBL5290216)
Affinity DataIC50: 78nMAssay Description:Inhibition of CDC42 activation in human MDA-MB-231 cells treated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed