BDBM50389856 CHEMBL2070870

SMILES Cc1[nH]c2ccccc2c1C(Nc1ccc(Cl)cc1)c1ccccc1Cl

InChI Key InChIKey=FYALZEQZMVNQCR-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50389856   

TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50389856(CHEMBL2070870)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of CMV-VDR expressed in human HEK293T cells assessed as inhibition of 1,25-(OH)2D3-induced CYP24A1 promoter transcription after 16 hrs by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50389856(CHEMBL2070870)
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD interaction to Alexa Fluor 647-labeled SRC2-3 by fluorescence polarization assay in presence of 0.01 mM 2-merc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50389856(CHEMBL2070870)
Affinity DataIC50: 8.22E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD interaction to Alexa Fluor 647-labeled SRC2-3 by fluorescence polarization assay in presence of 100 mM 2-merca...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50389856(CHEMBL2070870)
Affinity DataIC50: 5.45E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD interaction to Alexa Fluor 647-labeled SRC2-3 by fluorescence polarization assay in presence of 10 mM 2-mercap...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50389856(CHEMBL2070870)
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD interaction to SRC2-2 after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50389856(CHEMBL2070870)
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD interaction to DRIP-2 after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50389856(CHEMBL2070870)
Affinity DataIC50: 4.54E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD interaction to Alexa Fluor 647-labeled SRC2-3 by fluorescence polarization assay in presence of 1 mM 2-mercapt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50389856(CHEMBL2070870)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD interaction to Alexa Fluor 647-labeled SRC2-3 by fluorescence polarization assay in presence of 0.1 mM 2-merca...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50389856(CHEMBL2070870)
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD interaction to Alexa Fluor 647-labeled SRC2-3 after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed