BDBM50389497 CHEMBL1564869

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=HPTXLHAHLXOAKV-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50389497   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50389497(CHEMBL1564869)
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50389497(CHEMBL1564869)
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibition of human recombinant DNMT1 expressed in H19 cells assessed as inhibition of tritiated methyl incorporation from [3H]-labeled AdoMet into h...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50389497(CHEMBL1564869)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant DNMT3B expressed in baculovirus infected insect cells using CpG site containing internally quenched hairpin oligonucl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50389497(CHEMBL1564869)
Affinity DataIC50: 115nMAssay Description:Inhibition of DNMT (unknown origin) by densitometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrphan methyltransferase M.SssI(Spiroplasma monobiae strain MQ-1)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50389497(CHEMBL1564869)
Affinity DataKi:  230nMAssay Description:Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed