BDBM50389121 CHEMBL2064628

SMILES CN(C)C[C@@H](OC(=O)N1Cc2c(NC(=O)C(C)(C)C)[nH]nc2C1(C)C)c1ccccc1

InChI Key InChIKey=XVBWTZHNQZHFHR-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50389121   

TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataEC50:  4nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50: 450nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50: 227nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50: 170nMAssay Description:Inhibition of Erk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MARK1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50: 115nMAssay Description:Inhibition of MARK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed