BDBM50388957 CHEMBL2063722

SMILES COc1ccc(cc1)C(=O)N(C)c1nc(cs1)-c1cc(NC(C)C)ncn1

InChI Key InChIKey=SQRKGSZJVPRTRN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388957   

TargetMetabotropic glutamate receptor 1(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50388957(CHEMBL2063722)
Affinity DataIC50: 32.7nMAssay Description:Displacement of 4-[18F]fluoro-N-[4-(6-(isopropylamino)pyrimidin-4-yl)-1,3-thiazol-2-yl]-N-methylbenzamide from mGluR1 in Sprague-Dawley rat brain hom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50388957(CHEMBL2063722)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [11C]-ABP688 from mGluR5 in Sprague-Dawley rat brain homogenates after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50388957(CHEMBL2063722)
Affinity DataKi:  12.6nMAssay Description:Displacement of 4-[18F]fluoro-N-[4-(6-(isopropylamino)pyrimidin-4-yl)-1,3-thiazol-2-yl]-N-methylbenzamide from mGluR1 in Sprague-Dawley rat brain hom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed