BDBM50388719 CHEMBL2059860

SMILES Cc1ccc(cc1NC(=O)c1ccc(OCc2ccccn2)cc1)-c1c[nH]cn1

InChI Key InChIKey=VMANFLQBPGTNHR-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388719   

TargetSmoothened homolog(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388719(CHEMBL2059860)
Affinity DataEC50:  39.2nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388719(CHEMBL2059860)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388719(CHEMBL2059860)
Affinity DataEC50:  39nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed