BDBM50388677 CHEMBL2059314

SMILES O=C1COc2ccccc2N1CCCN1CCC(CC1)n1c2cnccc2[nH]c1=O

InChI Key InChIKey=OMSMDLGOLRRGGT-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388677   

TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50388677(CHEMBL2059314)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human M1 receptor expressed in CHO-K1 cells assessed as calcium mobilization for 6 mins by Calcium4-based stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50388677(CHEMBL2059314)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells after 30 mins by Rb+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50388677(CHEMBL2059314)
Affinity DataKi: >9.50E+3nMAssay Description:Displacement of [3H]raclopride from human D2L receptor expressed in CHO cells after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed