BDBM50388091 CHEMBL2058156

SMILES COc1cccc(c1)-n1nc(cc1-c1ccc(C2CCCCC2)c(Cl)c1)C(O)=O

InChI Key InChIKey=BNALUYKEGYUHQC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50388091   

TargetLysophosphatidic acid receptor 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50388091(CHEMBL2058156)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at LPA5 receptor in human isolated platelets assessed as inhibition of hexadecyl-LPA-induced platelet aggregation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50388091(CHEMBL2058156)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human recombinant LPA5 receptor expressed in rat RH7777 cells assessed as inhibition of hexadecyl-LPA-induced effectMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50388091(CHEMBL2058156)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at LPA5 receptor in human washed platelets assessed as inhibition of hexadecyl-LPA-induced platelet aggregation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50388091(CHEMBL2058156)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at LPA2 receptor in human isolated platelets assessed as inhibition of TRAP-induced platelet aggregation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50388091(CHEMBL2058156)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50388091(CHEMBL2058156)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of N-terminal polyhistidine-tagged human NSD2 expressed in baculovirus infected insect cell using SAM as substrate preincubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50388091(CHEMBL2058156)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of N-terminal polyhistidine-tagged recombinant human NSD1 (1538 to 2696 residues) expressed in baculovirus infected insect cell using SAM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50388091(CHEMBL2058156)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of N-terminal GST-fused recombinant human NSD3 (1021 to 1322 residues) expressed in Escherichia coli using SAM as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed