BDBM50387974 CHEMBL2057830

SMILES Oc1ccc(cc1)C1=NN2C(S1)=NC(=O)\C(=C\c1ccc(O)c(O)c1)C2=N

InChI Key InChIKey=FKGLDYLQFIXPLH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50387974   

TargetDual specificity protein phosphatase 4(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50387974(CHEMBL2057830)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine-phosphatase(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50387974(CHEMBL2057830)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50387974(CHEMBL2057830)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50387974(CHEMBL2057830)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of PRL3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50387974(CHEMBL2057830)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MEK2 using [gamma32P]ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387974(CHEMBL2057830)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of MEK1 using [gamma32P]ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387974(CHEMBL2057830)
Affinity DataIC50: 300nMAssay Description:Inhibition of PI3Kalpha using [gamma32P]ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed