BDBM50387329 CHEMBL2046645

SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(C2CC2)c(n1)C(=O)c1cccnc1N

InChI Key InChIKey=CQBKEYNDDXJYNG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50387329   

TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387329(CHEMBL2046645)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PKCtheta-mediated IL-2 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387329(CHEMBL2046645)
Affinity DataKi:  28nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387329(CHEMBL2046645)
Affinity DataKi:  255nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387329(CHEMBL2046645)
Affinity DataKi:  2.65E+3nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed