BDBM50386749 CHEMBL2046883

SMILES Cc1ccc(NC(=O)Nc2nnc(Sc3ncnc4cc(OCCCN5CCOCC5)ccc34)s2)cc1

InChI Key InChIKey=LKXFSTAQMOENSC-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50386749   

TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase Lck(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human LckMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human JAK3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human c-RafMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human RetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PLK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Pim1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human c-kitMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human IGF-1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human FLT4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human FLT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human FMSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed