BDBM50386733 CHEMBL2048936

SMILES NS(=O)(=O)N1CCc2cc(O)ccc2C1c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=IMCCJXZOAPRMSJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50386733   

TargetCarbonic anhydrase 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386733(CHEMBL2048936)
Affinity DataKi:  6.70nMAssay Description:Inhibition of human recombinant full length CA1-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386733(CHEMBL2048936)
Affinity DataKi:  6.70nMAssay Description:Inhibition of human recombinant full length CA2-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386733(CHEMBL2048936)
Affinity DataKi:  7.90nMAssay Description:Inhibition of human recombinant CA9 catalytic domain-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386733(CHEMBL2048936)
Affinity DataKi:  24.8nMAssay Description:Inhibition of human recombinant full length CA14-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50386733(CHEMBL2048936)
Affinity DataKi:  50.8nMAssay Description:Inhibition of human recombinant full length CA7-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed