BDBM50386425 CHEMBL2047529

SMILES CN(CCCOc1ccc2ccc(=O)oc2c1)Cc1cccc(OC(=O)NCCCCCCCN2CCOCC2)c1

InChI Key InChIKey=SBQAIYUBGADZLI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50386425   

LigandPNGBDBM50386425(CHEMBL2047529)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide preincubated for 20 mins before [14C]-anandamide addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386425(CHEMBL2047529)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of human recombinant FAAH in assessed as hydrolysis of [14C]-anandamide preincubated for 20 mins before [14C]-anandamide addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386425(CHEMBL2047529)
Affinity DataIC50: 119nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 120 mins before substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386425(CHEMBL2047529)
Affinity DataIC50: 11.2nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50386425(CHEMBL2047529)
Affinity DataIC50: 5.59E+3nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed