BDBM50385919 CHEMBL2042031

SMILES CC(Oc1cc(ccc1C(N)=O)-c1cc(cnc1N)-c1ccc(CN(C)C)cc1)c1ccccc1C(F)(F)F

InChI Key InChIKey=KPYFHKXGOZSVEX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50385919   

TargetSerine/threonine-protein kinase Nek2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50385919(CHEMBL2042031)
Affinity DataIC50: 120nMAssay Description:Inhibition of Nek2 using 5-FAM-KKLNRTLSVA-COOH as substrate after 1 hr by caliper methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50385919(CHEMBL2042031)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of MPS1 by caliper methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50385919(CHEMBL2042031)
Affinity DataIC50: 7.93E+3nMAssay Description:Inhibition of Aurora A kinase by caliper methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50385919(CHEMBL2042031)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of CDK2 by caliper methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50385919(CHEMBL2042031)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of Plk1 using 5-FAMRRRAGALMDASFEEQ- CONH2 as substrate after 75 mins by caliper methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed