BDBM50385616 CHEMBL2042239

SMILES CN1C(=O)N(Cc2cc(Cl)ccc2F)C(=O)[C@]11C(=O)N(CC(O)=O)c2ccc(Cl)cc12

InChI Key InChIKey=IDAMFVNNSWRUTJ-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50385616   

TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataIC50: 150nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change pretreated for 20 mins meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385616(CHEMBL2042239)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in CHO cells after 90 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed