BDBM50384559 CHEMBL2036456

SMILES Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccn1

InChI Key InChIKey=CFHJAKKKDPAQLU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384559   

TargetMAP kinase-activated protein kinase 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50384559(CHEMBL2036456)Copy SMILESCopy InChI

Affinity DataIC50: 30nMAssay Description:Inhibition of MK2 using 5TAMRA-KKLNRTLSVA-COOH as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by immobilized m...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetMAP kinase-activated protein kinase 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50384559(CHEMBL2036456)Copy SMILESCopy InChI

Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of MK2 in human THP1 cells assessed as inhibition of LPS-induced HSP27 Ser78 phosphorylation incubated for 60 mins prior to LPS-induction ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL