BDBM50384260 CHEMBL2030438

SMILES CC(C)S(=O)(=O)Cc1cc(nc(n1)-c1ccccn1)N1CCOCC1

InChI Key InChIKey=PWKJNZKOROTLHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384260   

LigandPNGBDBM50384260(CHEMBL2030438)
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384260(CHEMBL2030438)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed