BDBM50384257 CHEMBL2030444

SMILES COCc1cccc(c1)-c1nc(CS(C)(=O)=O)cc(n1)N1CCOCC1

InChI Key InChIKey=XZABOXATXRNWCX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384257   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50384257(CHEMBL2030444)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50384257(CHEMBL2030444)Copy SMILESCopy InChI

Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL