BDBM50383375 CHEMBL2030559::CHEMBL2069937::US10544104, Compound 99::US9765037, Compound 99

SMILES c1c2c(ncnc2n(n1)CC3CCNCC3)N

InChI Key InChIKey=WIWYTHZSXOQVGK-UHFFFAOYSA-N

Data  2 KI  5 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50383375   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383375(CHEMBL2069937 | CHEMBL2030559 | US9765037, Compoun...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SRC using Ac-EIYGEFKKK-OH as substrate after 60 mins by phosphor imaging methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383375(CHEMBL2069937 | CHEMBL2030559 | US9765037, Compoun...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ABL1(Human)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50383375(CHEMBL2069937 | CHEMBL2030559 | US9765037, Compoun...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383375(CHEMBL2069937 | CHEMBL2030559 | US9765037, Compoun...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ABL1(Human)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50383375(CHEMBL2069937 | CHEMBL2030559 | US9765037, Compoun...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383375(CHEMBL2069937 | CHEMBL2030559 | US9765037, Compoun...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ABL1(Human)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50383375(CHEMBL2069937 | CHEMBL2030559 | US9765037, Compoun...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed