BDBM50382459 CHEMBL2023986::US10196373, Compound 27NH
SMILES CN(CC(=O)N(Cc1ccc(cc1)-c1ccc(cc1)-c1ccc(cc1)C(N)=O)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1ccc(C)cc1
InChI Key InChIKey=KOVXOSJQVVRPFQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50382459
TargetSignal transducer and activator of transcription 3(Mouse)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
The Governing Council of The University of Toronto
US Patent
The Governing Council of The University of Toronto
US Patent
Affinity DataIC50: 4.30E+4nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Human)
University of Toronto
Curated by ChEMBL
University of Toronto
Curated by ChEMBL
Affinity DataKi: 4.80E+3nMAssay Description:Displacement of 5-carboxyfluorescein-labeled GpYLVLDKW from the STAT5b-SH2 domain after 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
The Governing Council of The University of Toronto
US Patent
The Governing Council of The University of Toronto
US Patent
Affinity DataKi: 8.40E+3nMAssay Description:Displacement of fluorescein-labeled phosphotyrosine-peptide derived from the interleukin-6 receptor subunit gp130 from the STAT3 after 15 mins by flu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Toronto
Curated by ChEMBL
University of Toronto
Curated by ChEMBL
Affinity DataKi: 9.50E+3nMAssay Description:Displacement of radioligand from the STAT1 after 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
The Governing Council of The University of Toronto
US Patent
The Governing Council of The University of Toronto
US Patent
Affinity DataKi: 1.67E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
The Governing Council of The University of Toronto
US Patent
The Governing Council of The University of Toronto
US Patent
Affinity DataKi: 1.67E+4nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair