BDBM50382224 CHEMBL2023841

SMILES [#6]C1([#6])[#6]-2=[#6]-3-[#6]=[#6]-4-[#6](-[#6]-[#6]-[#7+]-5=[#6]-4C([#6])([#6])c4cc(-[#6]-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#7]S(=O)(=O)c6cccc7cnccc67)-[#6](-[#7])=O)ccc-54)-[#8]-[#6]-3-[#6]-[#6]-[#7]-2-c2ccc(cc12)S([#6])(=O)=O

InChI Key InChIKey=PABLVBARXHFRFL-UHFFFAOYSA-N

Data  6 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50382224   

TargetcGMP-dependent protein kinase 1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382224(CHEMBL2023841)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to His6-tagged recombinant human PKG1alpha by fluorescence anisotropy assay in absence of cGMPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 2(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382224(CHEMBL2023841)
Affinity DataKd: <0.200nMAssay Description:Binding affinity to His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382224(CHEMBL2023841)
Affinity DataKd:  12nMAssay Description:Binding affinity to His6-tagged recombinant human MSK1 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382224(CHEMBL2023841)
Affinity DataKd:  7nMAssay Description:Binding affinity to His6-tagged recombinant human p70S6K by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382224(CHEMBL2023841)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to His6-tagged recombinant human ROCK1 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382224(CHEMBL2023841)
Affinity DataKd:  28nMAssay Description:Binding affinity to SGK1 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed