BDBM50381997 CHEMBL2022379

SMILES CC1CCCN(Cc2cc(Nc3nc(C)cn4c(cnc34)-c3cnn(CC(=O)Nc4ccncc4)c3)sn2)C1

InChI Key InChIKey=RIQJIFBZCJKJLX-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50381997   

TargetAurora kinase B(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50381997(CHEMBL2022379)
Affinity DataEC50:  83nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50381997(CHEMBL2022379)
Affinity DataIC50: 100nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381997(CHEMBL2022379)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50381997(CHEMBL2022379)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of RSK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50381997(CHEMBL2022379)
Affinity DataIC50: 108nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50381997(CHEMBL2022379)
Affinity DataIC50: 731nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50381997(CHEMBL2022379)
Affinity DataIC50: 12nMAssay Description:Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed