BDBM50381177 CHEMBL2018386

SMILES CCC[C@H](O)[C@H](CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(ccc1NC(=O)NCC)C(F)(F)F

InChI Key InChIKey=WMOYUNWNZFLZJG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50381177   

TargetC-C chemokine receptor type 2(Human)
National Heart and Lung Institute

Curated by ChEMBL
LigandPNGBDBM50381177(CHEMBL2018386)
Affinity DataIC50: 3.60nMAssay Description:Binding affinity to CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
National Heart and Lung Institute

Curated by ChEMBL
LigandPNGBDBM50381177(CHEMBL2018386)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50381177(CHEMBL2018386)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CCR2 in mouse monocytes assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50381177(CHEMBL2018386)
Affinity DataIC50: 86nMAssay Description:Binding affinity to mouse CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
National Heart and Lung Institute

Curated by ChEMBL
LigandPNGBDBM50381177(CHEMBL2018386)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125-I]MCP1 from CCR2 on human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed