BDBM50380728 CHEMBL2017835
SMILES Cc1cc(C)cc(C[C@H]2CCCCN2C(=O)CN2c3ccccc3-n3c(nnc3-c3ccccc3)[C@H](Cc3n[nH]c4ccccc34)C2=O)c1
InChI Key InChIKey=ZJGPYSQTJSMQNL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 51 hits for monomerid = 50380728
Affinity DataIC50: 71nMAssay Description:Displacement of [125I-CCK] from human CCK1R I6.51V, F6.52Y mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataEC50: 0.288nMAssay Description:Agonist activity at human CCK1R N2.61T mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at human CCK1R T3.28V, T3.29S mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 69nMAssay Description:Agonist activity at human CCK1R I6.51V, F6.52Y mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Agonist activity at human CCK1R L7.39H mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human CCK2R V6.51I, Y6.52F mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human CCK2R H7.39L mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R N2.61T mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R T3.28V, T3.29S mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R I6.51V, F6.52Y mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R L7.39H mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 0.813nMAssay Description:Displacement of [125I-CCK] from human CCK1R N2.61T mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [125I-CCK] from human CCK1R T3.28V, T3.29S mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R W6.48A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Displacement of [125I-CCK] from human CCK1R L7.39H mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-2] from human CCK2R V3.28T, S3.29T mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-2] from human CCK2R V6.51I, Y6.52F mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I-BDZ-2] from human CCK2R H7.39L mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-CCK] from human CCK2R T2.61N mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 302nMAssay Description:Displacement of [125I-CCK] from human CCK2R V3.28T, S3.29T mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-CCK] from human CCK2R V6.51I, Y6.52F mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Displacement of [125I-CCK] from human CCK2R H7.39L mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R M3.32A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataEC50: 25.4nMAssay Description:Agonist activity at human CCK1 receptor assessed as increase in CCK8-induced calcium release incubated in dark for 30 mins followed by light incubati...More data for this Ligand-Target Pair
Affinity DataIC50: 14.7nMAssay Description:Displacement of [125I]-CCK-2 from rat CCK1 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 20.3nMAssay Description:Displacement of [125I]-CCK-2 from human CCK1 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 955nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R V3.36A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-CCK] from human CCK1R M3.32A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I-CCK] from human CCK1R V3.36A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I-CCK] from human CCK1R W6.48A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataEC50: 3.30nMAssay Description:Agonist activity at human CCK1R V3.36A mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity at human CCK1R W6.48A mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 168nMAssay Description:Displacement of [125I]-BDZ-1 from wild-type rat CCK1R expressed in COS cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Rat)
Mayo Clinic
Curated by ChEMBL
Mayo Clinic
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]-BDZ-1 from rat CCK1R Ala-317,321,325 non dimerizing mutant expressed in COS cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-1] from wild-type human CCK1R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-2] from wild-type human CCK2R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataEC50: 0.470nMAssay Description:Agonist activity at wild-type human CCK1R expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 0.470nMAssay Description:Agonist activity at wild-type human CCK1R expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 692nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK2R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-1] from wild-type human CCK1R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-2] from wild-type human CCK2R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Displacement of [125I-BDZ-2] from wild-type human CCK2R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 214nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 214nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK2R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 912nMAssay Description:Displacement of [125I-BDZ-1] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Displacement of [125I-BDZ-1] from wild-type human CCK1R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [125I-BDZ-2] from wild-type human CCK2R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair