BDBM50380545 CHEMBL2019046

SMILES COc1cc(O)c2c(c1)oc(cc2=O)C(=O)NCCCCCCCCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=RRTQIJJHXQOLEO-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50380545   

TargetBeta-secretase 1(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50380545(CHEMBL2019046)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50380545(CHEMBL2019046)
Affinity DataIC50: 1nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50380545(CHEMBL2019046)
Affinity DataIC50: 2nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50380545(CHEMBL2019046)
Affinity DataIC50: 250nMAssay Description:Inhibition of bovine erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50380545(CHEMBL2019046)
Affinity DataIC50: 1nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50380545(CHEMBL2019046)
Affinity DataKi:  850nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed