BDBM50380468 CHEMBL2018763::N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N'-butylurea (11h)

SMILES CCCCNC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1

InChI Key InChIKey=ZXRPRSOBABQJOG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50380468   

TargetEpidermal growth factor receptor(Human)
Universit�� Lille Nord De France

LigandPNGBDBM50380468(CHEMBL2018763 | N-{4-[6,7-Dimethoxy-quinazolin-4-y...)
Affinity DataIC50: 3.06E+4nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Universit�� Lille Nord De France

LigandPNGBDBM50380468(CHEMBL2018763 | N-{4-[6,7-Dimethoxy-quinazolin-4-y...)
Affinity DataIC50: 8.03E+4nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Universit�� Lille Nord De France

LigandPNGBDBM50380468(CHEMBL2018763 | N-{4-[6,7-Dimethoxy-quinazolin-4-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR expressed in human A431 cells using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Universit�� Lille Nord De France

LigandPNGBDBM50380468(CHEMBL2018763 | N-{4-[6,7-Dimethoxy-quinazolin-4-y...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed