BDBM50380198 BONANNIONE A

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc2-[#8]-[#6@@H](-[#6]-[#6](=O)-c2c1-[#8])-c1ccc(-[#8])cc1

InChI Key InChIKey=RQIQBTNOARANRL-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50380198   

TargetAcetylcholinesterase(Human)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50380198(BONANNIONE A)
Affinity DataIC50: 9.15E+4nMAssay Description:Inhibition of human erythrocyte AChE assessed as acetylthiocholine iodide hydrolysis after 10 mins preincubation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50380198(BONANNIONE A)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of equine BChE assessed as butyrylthiocholine iodide hydrolysis after 10 mins preincubation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50380198(BONANNIONE A)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGE2 formation pre-incubated for 5 mins before arachidonic acid addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50380198(BONANNIONE A)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 formation pre-incubated for 5 mins before arachidonic acid addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50380198(BONANNIONE A)
Affinity DataKi:  2.22E+4nMAssay Description:Mixed type inhibition of equine BChE using butyrylthiocholine iodide as substrate by Lineweaver-Burk double-reciprocal-plot and dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50380198(BONANNIONE A)
Affinity DataKi:  1.21E+5nMAssay Description:Mixed type inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate by Lineweaver-Burk double-reciprocal-plot and dixon plot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed