BDBM50379838 CHEMBL2011750

SMILES NC(=N)c1ccc(OCc2ccc(COc3ccc(cc3I)C(N)=N)cc2)c(I)c1

InChI Key InChIKey=YGBZFHXWPPQSHR-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50379838   

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379838(CHEMBL2011750)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human thrombin-mediated blood clotting formation in presence of human fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50379838(CHEMBL2011750)
Affinity DataKi:  31nMAssay Description:Inhibition of human kallikrein 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50379838(CHEMBL2011750)
Affinity DataKi:  110nMAssay Description:Inhibition of amidase activity of bovine thrombin using BPVANA as substrate after 15 to 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcrosin(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50379838(CHEMBL2011750)
Affinity DataKi:  280nMAssay Description:Reversible competitive inhibition of boar spermatozoa acrosin using BzArgOEt as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetGlandular kallikrein(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50379838(CHEMBL2011750)
Affinity DataKi:  610nMAssay Description:Inhibition of porcine pancreatic kallikrein using BPPANA as substrate after 15 to 180 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed