BDBM50379241 CHEMBL2011479

SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1

InChI Key InChIKey=AADKPDGTJHDJAJ-UHFFFAOYSA-N

Data  1 KI  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50379241   

TargetMonoglyceride lipase(Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 290nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 275nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 288nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 680nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 280nMAssay Description:Inhibition of rat brain cytosolic MAGL assessed as [3H]-2-arachidonoyl glycerol hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant his-tagged MAGL expressed in Escherichia coli assessed as hydrolysis of 4-nitrophenyl acetate after 20 mins by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataIC50: 676nMAssay Description:Inhibition of rat brain membrane FAAH assessed as [3H]-anandamide hydrolysis after 10 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50379241(CHEMBL2011479)
Affinity DataKi:  4.00E+4nMAssay Description:Non-competitive inhibition of human recombinant MAGL assessed as 7-hydroxycoumarin level using umbelliferyl arachidonate as substrate by luminescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed